Propensity Score–Adjusted Comparison of Long-Term Outcomes Among Revascularization Strategies For Critical Limb Ischemia

Jihad A. Mustapha, Barry T. Katzen, Richard F. Neville, Robert A. Lookstein, Thomas Zeller, Larry E. Miller, Teresa R. Nelson, Michael R. Jaff, On behalf of the Board of the CLI Global Society


Few studies have compared long-term outcomes among specific treatment modalities for critical limb ischemia. The aim of this study was to compare long-term outcomes with percutaneous transluminal angioplasty (PTA), stent placement, atherectomy, or surgical bypass in patients diagnosed with critical limb ischemia.


In this observational study using Medicare claims data, we identified incident cases with a primary critical limb ischemia diagnosis who received PTA, stent placement, atherectomy, or surgical bypass. We used propensity score weighting to determine the association of treatment type with all-cause mortality and major (above ankle) amputation over 4 years follow-up.

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