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Learn how top leaders are preventing amputation and death due to CLI.

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The CLI Global Society's mission is to improve quality of life by preventing amputations and death due to Critical Limb Ischemia.

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Members have on-demand access to a video education series from the top physicians in our industry, including live cases and a step-by-step guide of recognizing, diagnosing, treatment, and therapies for Critical Limb Ischemia.


Preoperative C-Reactive Protein Levels Predict Readmission Following Elective Vascular Surgery

C-reactive protein (CRP) levels may be reduced with long-term administration of ubiquinone (CoQ10) in patients with chronic ischemic heart disease, but the impact of a short-term period of administration in patients undergoing ele… read article preview

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Among an estimated 9-20 million adults with PAD in the United States, at least 11% suffer from CLI. This is considered an underestimation.

Worldwide, 202 million adults have PAD which has a higher prevalence than ischemic heart disease, heart failure, Alzheimer’s, dementia, cancer, and HIV/AIDS.

Lower extremity PAD manifests as CLI in nearly 1 million Medicare patients per year with an estimated annual cost of over 3 billion dollars.

One in 190 Americans (1.6 million) are living with loss of a limb. Unchecked, this number may more than double by 2050 to 3.6 million.