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Learn how top leaders are preventing amputation and death due to CLI.

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The CLI Global Society's mission is to improve quality of life by preventing amputations and death due to Critical Limb Ischemia.

Multidisciplinary CLI Network

MCLIN is an accredited LIVE monthly discussion for complex case studies and complications dedicated to Critical Limb Ischemia and is an exclusive member-only benefit for CLI Global Society members.

The CLI Global Society Multidisciplinary Roundtable Discussion on BEST-CLI: Implications of the Available Data

The long-awaited results of the BEST-CLI trial were recently published in the New England Journal of Medicine and presented at the 2022 American Heart Association Scientific Sessions. This prospective, randomized trial was spon… read article preview

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Abbott - CLI Global Society Industry Partner BD Health - Europe Chapter - CLI Global Society Industry Partner Boston Scientific - CLI Global Society Industry Partner CSI - CLI Global Society Industry Partner Cordis - CLI Global Society Industry Partner Medtronic - CLI Global Society Industry Partner Phillips - CLI Global Society Industry Partner Reflow Medical - CLI Global Society Industry Partner

Among an estimated 9-20 million adults with PAD in the United States, at least 11% suffer from CLI. This is considered an underestimation.

Worldwide, 202 million adults have PAD which has a higher prevalence than ischemic heart disease, heart failure, Alzheimer’s, dementia, cancer, and HIV/AIDS.

Lower extremity PAD manifests as CLI in nearly 1 million Medicare patients per year with an estimated annual cost of over 3 billion dollars.

One in 190 Americans (1.6 million) are living with loss of a limb. Unchecked, this number may more than double by 2050 to 3.6 million.